Two more remotely operated underwater vehicles are searching for the missing Titanic tourist submersible, the Coast Guard said early Thursday, the estimated deadline for when the five passengers may have run out of oxygen in the small vessel.

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The accelerating search efforts come as an updated prediction by the Coast Guard said the Titan submersible was likely to run out of oxygen roughly around 7 a.m. ET Thursday. It initially had 96 hours of oxygen for a crew of five. Experts have noted that the estimates are imprecise.

“People’s will to live really needs to be accounted for as well, so we’re continuing to search and proceed with rescue efforts by bringing this new capability online this morning,” Rear Adm. John Mauger of the U.S. Coast Guard told the TODAY show early Thursday.

The ROVs on site are able to attach rescue lines, and personnel with deep-sea medical expertise are moving onto the scene, he said. Teams worked through the night, he said.

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