(ASSOCIATED PRESS) Yemen’s Houthi rebels vowed fierce retaliation Friday for American and British strikes against them, further raising the prospect of a wider conflict in a region already beset by Israel’s war in Gaza.

The bombardment — launched in response to a recent campaign of drone and missile attacks on commercial ships in the vital Red Sea — killed at least five people and wounded six, the Houthis said. The U.S. said the strikes took aim at more than 60 targets in 16 different locations across Houthi-controlled areas of Yemen.

As the bombing lit the predawn sky over multiple sites held by the Iranian-backed rebels, it forced the world to again focus on Yemen’s yearslong war, which began when the Houthis seized the country’s capital.

Since November, the rebels have repeatedly targeted ships in the Red Sea, saying they were avenging Israel’s offensive in Gaza against Hamas. But they have frequently targeted vessels with tenuous or no clear links to Israel, imperiling shipping in a key route for global trade and energy shipments.

The Houthis’ military spokesman, Brig. Gen. Yahya Saree, said in a recorded address that the strikes would “not go unanswered or unpunished.”

The British military’s United Kingdom Maritime Trade Operations, which oversees Mideast waters, reported on Friday evening a new missile attack off Yemen. It said the missile was fired toward a ship some 90 miles southeast of Aden, Yemen, while the ship was being followed by three small vessels. The shipmaster reported missiles landing in the water 400 to 500 meters away, but they caused no injures or damage, the organization said.

“Vessels are advised to transit with caution,” it warned.

Though the Biden administration and its allies have tried to calm tensions in the Middle East for weeks and prevent any wider conflict, the strikes threatened to ignite one.

Saudi Arabia — which supports the government-in-exile that the Houthis are fighting — quickly sought to distance itself from the attacks as it seeks to maintain a delicate détente with Iran and a cease-fire it has in Yemen.

The Houthis said strikes on regions of Yemen under their control killed five and wounded six from the rebels’ military forces. It remained unclear how extensive the damage was, though the Houthis said at least five sites, including airfields, had been attacked.

U.S. Air Forces Central Command said the strikes focused on the Houthi’s command and control nodes, munition depots, launching systems, production facilities and air defense radar systems. The strikes involved more than 100 precision-guided munitions including air-launched missiles and ship-and submarine launched Tomahawk land attack missiles.

The United Kingdom said strikes hit a site in Bani allegedly used by the Houthis to launch drones and an airfield in Abbs used to launch cruise missiles and drones.

Meanwhile, the U.S. Treasury Department on Friday announced it imposed sanctions on two firms in Hong Kong and the United Arab Emirates for allegedly shipping Iranian commodities on behalf of Iran-based Houthi financial facilitator Sa’id al-Jamal. Four vessels owned by the firms were also identified as blocked property.

Hussein al-Ezzi, a Houthi official in their Foreign Ministry, that “America and Britain will undoubtedly have to prepare to pay a heavy price and bear all the dire consequences of this blatant aggression.”

The Red Sea route is a crucial waterway, and attacks there have caused severe disruptions to global trade. Benchmark Brent crude oil traded up some 4% Friday at over $80 a barrel. Tesla, meanwhile, said it would temporarily halt most production at its German factory because of attacks in the Red Sea.

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