Research suggests COVID infection plus vaccination provides the strongest protection against a wide range of variants, possibly for a long time.

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As with most illnesses, contracting COVID-19 provides immune “memory” that helps protect against a future infection. But it’s still unclear how sick a person has to get with COVID-19 to develop enough immune memory to be protective and for how long. That’s why the Centers for Disease Control and Prevention recommends even people who have had COVID-19 get vaccinated against it.

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