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It’s time to do some spring cleaning — of your medicine cabinet.

Some of those medications have been sitting there for years, and the science around them may have quietly changed. Here are five that deserve a second look, says Dr. Trisha Pasricha, a physician at Beth Israel Deaconess Medical Center, an assistant professor of medicine at Harvard Medical School and The Washington Post’s Ask a Doctor columnist.

But before you stop taking them, you should have a discussion with your doctor, just to be sure.

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